PUBLICATIONS


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2020

  • Scull, E. M.; Bandari, C.; Johnson, B. P.; Gardner, E. D.; Tonelli, M.; You, J.; 1, Cichewicz, R. H.; Singh, S. Chemoenzymatic synthesis of daptomycin analogs active against daptomycin-resistant strains. Applied Microbiology and Biotechnology, 2020. Epub ahead of print. PMID: 32725322. VIEW
  • Pederson, P. J.; Cai, S.; Carver, C.; Powell, D. R.;  Risinger, A. L.; Grkovic, T.; O’Keefe, B. R.; Mooberry, S. L.;  Cichewicz, R. H. Triple-negative breast cancer cells exhibit differential sensitivity to cardenolides from Calotropis gigantea. Journal of Natural Products, 2020, 83 (7), 2269-2280. PMID: 32649211. VIEW
  • Kil, Y. S.; Risinger, A. L.;  Petersen, C. L.; Liang, H.; Grkovic, T.;  O’Keefe, B. R.; Mooberry, S. L.;  Cichewicz, R. H. Using the cancer dependency map to identify the mechanism of action of a cytotoxic alkenyl derivative from the fruit of Choerospondias axillaris. Journal of Natural Products, 2020, 83 (3), 584-592. PMID: 32105068. VIEW
  • Kil, Y. S.; Risinger, A. L.; Petersen, C. L.; Mooberry, S. L.; Cichewicz, R. H. Leucinostatins from Ophiocordyceps spp. and Purpureocillium spp. demonstrate selective antiproliferative effects in cells representing the luminal androgen receptor subtype of triple negative breast cancer. Journal of Natural Products, 2020, 83 (6), 2010-2024. PMID: 32510949. VIEW
  • Tran, T. D.; Wilson, B. A. P.; Henrich, C. J.; Wendt, K. L.; King, J.; Cichewicz, R. H.; Stchigel, A. M.; Miller, A. N.; O’Keefe, B. R.; Gustafson, K. R. Structure elucidation and absolute configuration of metabolites from the soil-derived fungus dictyosporium digitatum using spectroscopic and computational methods. Phytochemistry, 2020, 173, 112278. PMID: 32078832. VIEW
  • Nguyen, T. D.; Lesani, M.; Forrest, I.; Lan, Y; Dean, D. A.; Gibaut, Q. M. R.; Guo, Y.; Hossain, E.; Olvera, M.; Panlilio, H.; Parab, A. R.; Wu, C.; Bernatchez, J. A.; Cichewicz, R. H.; McCall, L. I. Local phenomena shape backyard soil metabolite composition. Metabolites, 2020, 10 (3), E86. PMID: 32121389. VIEW

2019

  • Dai, W.; Sandoval, I. T.; Cai, S.; Smith, K. A.; Delacruz, R. G. C.; Boyd, K. A.; Mills, J. J.; Jones, D. A.; Cichewicz, R. H. Inhibitory arisugacins L-Q from a Penicillium sp. isolate obtained through a citizen science initiative and their activities in a phenotype-based zebrafish assay. Journal of Natural Products, 2019, 82 (9), 2627-2637. PMID: 31433188. VIEW
  • Du, L.; Munteanu, C.; King, J. B.; Frantz, D. E.; Cichewicz, R. H. An electrophilic natural product provides a safe and robust odor neutralization approach to counteract malodorous organosulfur metabolites encountered in skunk spray. Journal of Natural Products, 2019, 82 (7), 1989-1999. PMID: 31273979. VIEW
  • King, J. B.; Carter, A. C.; Dai, W.; Lee, J. W.; Kil, Y. S.; Du, L.; Helff, S. K.; Cai, S.; Huddle, B. C.; Cichewicz, R. H. Design and application of a high-throughput, high-content screening system for natural product inhibitors of the human parasite Trichomonas vaginalisACS Infectious Diseases, 2019, 5 (8), 1456-1470. PMID: 31265248. VIEW
  • Carter, A. C.; King, J. B.; Mattes, A. O.; Cai, S.; Singh, N.; Cichewicz, R. H. Natural-product-inspired compounds as countermeasures against the liver carcinogen aflatoxin B1Journal of Natural Products, 2019, 82 (6), 1694-1703. PMID: 31136174. VIEW
  • Carter, A. C.; Petersen, C. L.; Wendt, K. L.; Helff, S. K.; Risinger, A. L.; Mooberry, S. L.; Cichewicz, R. H. In situ ring contraction and transformation of the rhizoxin macrocycle through an abiotic pathwayJournal of Natural Products, 2019, 82 (4), 886-894. PMID: 30865445. VIEW
  • Cai, S.; Risinger, A. L.; Petersen, C. L.; Grkovic, T.; O’Keefe, B. R.; Mooberry, S. L.; Cichewicz, R. H. Anacolosins A-F and corymbulosins X and Y, clerodane diterpenes from Anacolosa Clarkii exhibiting cytotoxicity toward pediatric cancer cell linesJournal of Natural Products, 2019, 82 (4), 928-936. PMID: 30830773. VIEW
  • Du, L.; Risinger, A. L.; Yee, S. S.; Ola, A. R. B.; Zammiello, C. L.; Cichewicz, R. H.; Mooberry, S. L. Identification of C-6 as a new site for linker conjugation to the taccalonolide microtubule stabilizersJournal of Natural Products, 2019, 82 (3), 583-588. PMID: 30799622. VIEW
  • Tran, T. D.; Wilson, B. A. P.; Henrich, C. J.; Staudt, L. M.; Krumpe, L. R. H.; Smith, E. A.; King, J.; Wendt, K. L.; Stchigel, A. M.; Miller, A. N.; Cichewicz, R. H.; O’Keefe, B. R.; Gustafson, K. R. Secondary metabolites from the fungus Dictyosporium sp. and their MALT1 inhibitory activitiesJournal of Natural Products, 2019, 82 (1), 154-162. PMID: 30600998. VIEW

2018

  • Ola, A. R. B.; Risinger, A. L.; Du, L. Zammiello, C.; Peng, J.; Cichewicz, R. H.; Mooberry, S. L. Taccalonolide microtubule stabilizers generated using semisynthesis define the effects of mono acyloxy moieties at C-7 or C-15 and disubstitutions at C-7 and C-25Journal of Natural Products, 2018, 81 (3), 579-593. PMID: 29360362. VIEW
  • Wahl, H. E.; Raudabaugh, D. B.; Bach, E. M.; Bone, T. S.; Luttenton, M. R.; Cichewicz, R. H.; Miller, A. N. What lies beneath? Fungal diversity at the bottom of Lake Michigan and Lake SuperiorJournal of Great Lakes Research, 2018, 44 (2), 263-270. PMID: 29736110. VIEW
  • Mattes, A.; Russell, D.; Tishchenko, E.; Yanzhou, L.; Cichewicz, R. H.; Robinson, S. J. Application of 19F quantitative NMR to pharmaceutical analysis. Concepts in Magnetic Resonance, 2018. 45A (5), E21422. VIEW
  • Graef, J. L.; Rendina-Ruedy, E.; Crockett, E. K.; Ouyang, P.; King, J. B.; Cichewicz, R. H.; Lucas, E. A.; Smith, B. J. Select polyphenolic fractions from dried plum enhance osteoblast activity through BMP-2 signalingJournal of Nutritional Biochemistry, 2018, 55, 59-67. PMID: 29413490. VIEW

2017

  • Graef, J. L.; Rendina-Ruedy, E.; Crockett, E. K.; Ouyang, P.; King, J. B.; Cichewicz, R. H.; Lucas, E. A.; Smith, B. J. Osteoclast differentiation is downregulated by select polyphenolic fractions from dried plum via suppression of MAPKs and Nfatc1 in Mouse C57BL/6 primary bone marrow cellsCurrent Developments in Nutrition, 2017, 1 (10), E000406. PMID: 29955675. VIEW
  • Robles, A. J.; McCowen ,S.; Cai, S.; Glassman, M.; Ruiz, F. 2nd; Cichewicz, R. H.; McHardy, S. F.; Mooberry, S. L. Structure-activity relationships of new natural product-based diaryloxazoles with selective activity against androgen receptor-positive breast cancer cellsJournal of Medicinal Chemistry, 2017, 60 (22), 9275-9289. PMID: 29053266. VIEW
  • Du, L.; Risinger, A. L.; Mitchell, C. A.; You, J.; Stamps, B. W.; Pan, N.; King, J. B.; Bopassa, J. C.; Judge, S. I. V.; Yang, Z.; Stevenson, B. S.; Cichewicz, R. H. Unique amalgamation of primary and secondary structural elements transform peptaibols into potent bioactive cell-penetrating peptidesProceedings of National Academy of Sciences, 2017, 114 (43), E8957-E8966. PMID: 29073092. VIEW
  • Cho, N.; Ranson, T. T.; Sigmund, J.; Tran, T.; Cichewicz, R. H.; Goetz, M.; Beutler, J. A. Growth inhibition of colon cancer and melanoma cells by versiol derivatives from a Paraconiothyrium speciesJournal of Natural Products, 2017, 80 (7), 2037-2044. PMID: 28654255. VIEW
  • Motley, J. L.; Stamps, B. W.; Mitchell, C. A.; Thompson, A. T.; Cross, J.; You, J.; Powell, D. R.; Stevenson, B. S.; Cichewicz, R. H. Correction to opportunistic sampling of roadkill as an entry point to accessing natural products assembled by bacteria associated with non-anthropoidal mammalian microbiomes. Journal of Natural Products, 2017, 80 (4), 1233. PMID: 28339197. VIEW
  • Cichewicz, R. H.; Cragg, G. M.; Linington, R. G.: Wright, A. E. Special issue in honor of Professor Phil CrewsJournal of Natural Products, 2017, 80 (3), 579-581. PMID: 28335607. VIEW
  • Risinger, A. L.; Li, J.; Du, L.; Benavides, R.; Robles, A. J.; Cichewicz, R. H.; Kuhn, J. G.; Mooberry, S. L. Pharmacokinetic analysis and in vivo antitumor efficacy of taccalonolides AF and AJJournal of Natural Products, 2017, 80 (2), 409-414. PMID: 28112516. VIEW
  • Motley, J.L.; Stamps, B. W.; Mitchell, C. A.; Thompson, A. T.; Cross, J.; You, J.; Powell, D. R.; Stevenson, B. S.; Cichewicz, R. H. Opportunistic sampling of roadkill as an entry point to accessing natural products assembled by bacteria associated with non-anthropoidal mammalian microbiomesJournal of Natural Products, 2017, 80 (3), 598-608. PMID: 28335605. VIEW

2016

  • Garg, N.; Zeng Y.; Edlund, A.; Melnik, A. V.; Sanchez, L. M.; Mohimani, H.; Gurevich, A.; Miao, V.; Schiffler, S.; Lim, Y. W.; Luzzatto-Knaan, T.; Cai, S.; Rohwer, F.; Pevzner, P. A.; Cichewicz, R. H.; Alexandrov, T.; Dorrestein, P. C. Spatial molecular architecture of the microbial community of a Peltigera lichenmSystems, 2016, 1 (6), 00139-16. PMID: 28028548. VIEW
  • Robles, A. J.; Du, L.; Cichewicz, R. H.; Mooberry, S. L. Maximiscin induces DNA damage, activates DNA damage response pathways, and has selective cytotoxic activity against a subtype of triple-negative breast CancerJournal of Natural Products, 2016, 79 (7), 1822-7. PMID: 27310425. VIEW
  • Foxley M. A.; Friedline, A. W.; Jensen, J. M.; Nimmo, S. L.; Scull, E. M.; King, J. B.; Strange, S.; Xiao, M. T.; Smith, B. E.; Thomas Iii, K. J.; Glatzhofer, D. T.; Cichewicz, R. H.; Rice, C. V. Efficacy of ampicillin against methicillin-resistant Staphylococcus aureus restored through synergy with branched poly(ethylenimine)Journal of Antibiotics (Tokyo), 2016, 69 (12), 871-8. PMID: 27189119. VIEW
  • Robles, A. J.; Cai, S.; Cichewicz, R. H.; Mooberry, S. L. Selective activity of deguelin identifies therapeutic targets for androgen receptor-positive breast cancerBreast Cancer Research and Treatment, 2016, 157 (3), 475-88. PMID: 27255535. VIEW
  • Van Kanegan, M. J.; Dunn, D. E.; Kaltenbach, L. S.; Shah, B.; He, D. N.; McCoy, D. D.; Yang, P.; Peng, J.; Shen, L.; Du, L.; Cichewicz, R. H.; Newman, R. A.; Lo, D. C. Dual activities of the anti-cancer drug candidate PBI-05204 provide neuroprotection in brain slice models for neurodegenerative diseases and strokeScientific Reports, 2016, 6, 25626. PMID: 27172999. VIEW
  • Du, L.; You, J.; Nicholas, K. M.; Cichewicz, R. H.* Chemoreactive natural products afford resistance against disparate antibiotics and toxinsAngewandte Chemie International Edition, 2016, 55 (13), 4220-5. PMID: 26928999. VIEW
  • Shaffer, C. V.; Cai, S.; Peng, J.; Robles, A. J.; Hartley, R. M.; Powell, D. R.; Du, L.; Cichewicz, R. H.; Mooberry, S. L. Texas native plants yield compounds with cytotoxic activities against prostate cancer cellsJournal of Natural Products, 2016, 79 (3), 531-40. PMID: 26785306. VIEW

2015

  • Stamps, B. W.; Du, L.; Mitchell, C. A.; Cichewicz, R. H.; Stevenson, B. S. Draft genomes of two Sordariomycete fungi that produce novel secondary metabolites. Genome Announcements, 2015, 3 (2), E00291-15. PMID: 25883292. VIEW
  • Du, L.; Robles, A. J.; King, J. B.; Powell, D. R.; Miller, A. N.; Mooberry, S. L.; Cichewicz, R. H. Corrigendum: Crowdsourcing natural products discovery to access uncharted dimensions of fungal metabolite diversity. Angewandte Chemie International Edition, 2015, 54 (23), 6671. PMID: 26055200. VIEW
  • Cai, S.; Risinger, A. L.; Nair, S.; Peng, J.; Anderson, T. J.; Du, L.; Powell, D. R.; Mooberry, S. L.; Cichewicz, R. H. Identification of compounds with efficacy against malaria parasites from common North American plantsJournal of Natural Products, 2015, 79 (3), 490-8. PMID: 26722868. VIEW
  • Niu, G.; Wang, B.; Zhang, G.; King, J. B.; Cichewicz, R. H.; Li, J. Targeting mosquito FREP1 with a fungal metabolite blocks malaria transmission. Scientific Reports, 2015, 5, 14694. PMID: 26437882. VIEW
  • Wang, B.; Park, E. M.; King, J. B.; Mattes, A. O.; Nimmo, S. L.; Clendinen, C.; Edison, A. S.; Anklin, C.; Cichewicz, R. H. Transferring fungi to a deuterium-enriched medium results in assorted, conditional changes in secondary metabolite productionJournal of Natural Products, 2015, 78 (6), 1415-21. PMID: 26061478. VIEW

2014

  • Du, L.; King, J. B.; Cichewicz, R. H. Chlorinated polyketide obtained from a Daldinia sp. treated with the epigenetic modifier suberoylanilide hydroxamic acid. Journal of Natural Products, 2014, 77 (11), 2454-8. PMID:25338315. VIEW
  • Wang, B.; You, J.; King, J. B.; Cai, S.; Park, E.; Powell, D. R.; Cichewicz, R. H. Polyketide glycosides from Bionectria ochroleuca inhibit Candida albicans biofilm formation. Journal of Natural Products, 2014, 77 (10), 2273-9. PMID 25302529. VIEW
  • Cai, S.; King, J. B.; Du, L.; Powell, D. R.; Cichewicz, R. H. Bioactive sulfur-containing sulochrin dimers and other metabolites from an Alternaria sp. isolate from a Hawaiian soil sample. Journal of Natural Products, 2014, 77 (10), 2280-7. PMID 25265160. VIEW
  • Du, L.; Risinger, A. L., King, J.B.; Powell, D.R.; Cichewicz, R.H. A potent HDAC inhibitor, 1-alaninechlamydocin, from a Tolypocladium sp. induces G2/M cell cycle arrest and apoptosis in MIA PaCa-2 cells. Journal of Natural Products, 2014, 77 (7), 1753-7. PMID 24999749. VIEW
  • Williams, R. B.; Du, L.; Norman, V. L.; Goering, M. G.; O’Neil-Johnson, M.; Woodbury, S.; Albrecht, M. A.; Powell, D. R.; Cichewicz, R. H.; Eldridge, G. R.; Starks, C. M. Diterpenes from the endangered goldenrod Solidago shortii. Journal of Natural Products, 2014, 77 (6), 1438-1444. PMID 24922615. VIEW
  • Du, L.; Robles, A. J.; King, J. B.; Mooberry, S. L.; Cichewicz, R. H. Cytotoxic dimeric epipolythiodiketopiperazines from the ascomycetous fungus Preussia typharum. Journal of Natural Products, 2014, 77 (6), 1459-1466. PMID 24893224. VIEW
  • Theodore, C. M.; Stamps, B. W.; King, J. B.; Price, L. S.; Powell, D. R.; Stevenson, B. S.; Cichewicz, R. H. Genomic and metabolomic insights into the natural product biosynthetic diversity of a feral-hog-associated Brevibacillus laterosporus strain. PLoS One, 2014, 9 (3), E90124. PMID: 24595070. VIEW
  • Du, L.; Robles, A. J.; King, J. B.; Powell, D. R.; Miller, A. N.; Mooberry, S. L.; Cichewicz, R. H. Crowdsourcing natural products discovery to access uncharted dimensions of fungal metabolite diversity. Angewandte Chemie International Edition, 2014, 53 (3), 804-9. PMID: 24285637. VIEW

2013

  • Cai S., Du L.; Gerea A. L.; King J. B.; You J.; Cichewicz R. H. Spiro fused diterpene-indole alkaloids from a creek-bottom-derived Aspergillus terreus. Organic Letters, 2013, 15 (16), 4186-4189. PMID: 23924243. VIEW
  • Liu, X. H.; Miao, F. P.; Qiao, M. F.; Cichewicz, R. H.; Ji, N. Y. Terretonin, ophiobolin, and drimane terpenes with absolute configurations from an algicolous Aspergillus ustus. RSC Advances, 2013, 3 (2), 588-595. 
  • You, J. L.; Du, L.; King, J. B.; Hall, B.E.; Cichewicz, R. H. Small-molecule suppressors of Candida albicans biofilm formation synergistically enhance the antifungal activity of amphotericin B against clinical Candida isolates. ACS Chemical Biology, 2013, 8, 840-848. PMID: 23387427. VIEW

2012

  • Wang, X. R.; You, J. L.; King, J. B.; Powell, D. R.; Cichewicz, R. H. Waikialoid A suppresses hyphal morphogenesis and inhibits biofilm development in pathogenic Candida albicans. Journal of Natural Products, 2012, 75 (4), 707-715. PMID: 22400916. VIEW
  • Wang, X. R.; Du, L.; You, J. L.; King, J. B.; Cichewicz, R. H. Fungal biofilm inhibitors from a human oral microbiome-derived bacterium. Organic & Biomolecular Chemistry, 2012, 10 (10), 2044-2050. PMID: 22281750. VIEW
  • Theodore, C. M.; King, J. B.; You, J. L.; Cichewicz, R. H. Production of cytotoxic glidobactins/luminmycins by Photorhabdus asymbiotica in liquid media and live crickets. Journal of Natural Products, 2012, 75 (11), 2007-2011. PMID: 23095088. VIEW
  • Miao, F. P.; Li, X. D.; Liu, X. H.; Cichewicz, R. H.; Ji, N. Y. Secondary metabolites from an algicolous Aspergillus versicolor strain. Marine Drugs, 2012, 10 (1), 131-139. PMID: 22363226. VIEW
  • Jiang, M.; Wang, J.; Fu, J.; Du, L.; Jeong, H.; West, T.; Xiang, L.; Peng, Q.; Hou, Z.; Cai, H.; Seredenina, T.; Arbez, N.; Zhu, S.; Sommers, K.; Qian, J.; Zhang, J.; Mori, S.; Yang, X. W.; Tamashiro, K. L. K.; Aja, S.; Moran, T. H.; Luthi-Carter, R.; Martin, B.; Maudsley, S.; Mattson, M. P.; Cichewicz, R. H.; Ross, C. A.; Holtzman, D. M.; Krainc, D.; Duan, W. Neuroprotective role of Sirt1 in mammalian models of Huntington’s disease through activation of multiple Sirt1 targets. Nature Medicine, 2012, 18 (1), 153-158. PMID: 22179319. VIEW
  • Gerea, A. L.; Branscum, K. M.; King, J. B.; You, J.; Powell, D. R.; Miller, A. N.; Spear, J. R.; Cichewicz, R. H. Secondary metabolites produced by fungi derived from a microbial mat encountered in an iron-rich natural spring. Tetrahedron Letters, 2012, 53 (32), 4202-4205. PMID: 22844162. VIEW
  • Fu, J.; Jin, J.; Cichewicz, R. H.; Hageman, S. A.; Ellis, T. K.; Xiang, L.; Peng, Q.; Jiang, M.; Arbez, N.; Hotaling, K.; Ross, C. A.; Duan, W. Trans-(−)-ϵ-viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated protein kinase (AMPK), and protects cells in models of Huntington disease. Journal of Biological Chemistry, 2012, 287 (29), 24460-24472. PMID: 22648412. VIEW
  • Du, L.; King, J. B.; Morrow, B. H.; Shen, J. K.; Miller, A. N.; Cichewicz, R. H. Diarylcyclopentendione metabolite obtained from a Preussia typharum isolate procured using an unconventional cultivation approach. Journal of Natural Products, 2012, 75 (10), 1819-1823. PMID: 23046341. VIEW

2011

  • Joyner, P. M.; Waters, A. L.; Williams, R. B.; Powell, D. R.; Janakiram, N. B.; Rao, C. V.; Cichewicz, R. H. Briarane diterpenes diminish COX-2 expression in human colon adenocarcinoma cells. Journal of Natural Products, 2011, 74 (4), 857-861. PMID: 21438584. VIEW
  • Joyner, P. M.; Cichewicz, R. H. Bringing natural products into the fold – exploring the therapeutic lead potential of secondary metabolites for the treatment of protein-misfolding-related neurodegenerative diseases. Natural Product Reports, 2011, 28 (1), 26-47. PMID: 20927454. VIEW
  • Henrikson, J. C.; Ellis, T. K.; King, J. B.; Cichewicz, R. H. Reappraising the structures and distribution of metabolites from black aspergilli containing uncommon 2-benzyl-4H-pyran-4-one and 2-benzylpyridin-4(1H)-one systems. Journal of Natural Products, 2011, 74 (9), 1959-1964. PMID: 21854017. VIEW

2010

  • Wu, C. G.; Cichewicz, R.; Li, Y. H.; Liu, J. M.; Roe, B.; Ferretti, J.; Merritt, J.; Qi, F. X. Genomic island TnSmu2 of Streptococcus mutans harbors a nonribosomal peptide synthetase-polyketide synthase gene cluster responsible for the biosynthesis of pigments involved in oxygen and H2O2  tolerance. Applied and Environmental Microbiology, 2010, 76 (17), 5815-5826. PMID: 20639370. VIEW
  • Wang, X.; Sena Filho, J. G.; Hoover, A. R.; King, J. B.; Ellis, T. K.; Powell, D. R.; Cichewicz, R. H. Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an Atlantic-Forest-soil-derived Penicillium citreonigrumJournal of Natural Products, 2010, 73 (5), 942-948. PMID: 20450206. VIEW
  • Joyner, P. M.; Matheke, R. M.; Smith, L. M.; Cichewicz, R. H. Probing the metabolic aberrations underlying mutant huntingtin toxicity in yeast and assessing their degree of preservation in humans and mice. Journal of Proteome Research, 2010, 9 (1), 404-412. PMID: 19908918. VIEW
  • Joyner, P. M.; Liu, J.; Zhang, Z.; Merritt, J.; Qi, F.; Cichewicz, R. H. Mutanobactin A from the human oral pathogen Streptococcus mutans is a cross-kingdom regulator of the yeast-mycelium transition. Organic & Biomolecular Chemistry, 2010, 8 (24), 5486-5489. PMID: 20852771. VIEW
  • Henrikson, J. C.; Gharfeh, M. S.; Easton, A. C.; Easton, J. D.; Glenn, K. L.; Shadfan, M.; Mooberry, S. L.; Hambright, K. D.; Cichewicz, R. H. Reassessing the ichthyotoxin profile of cultured Prymnesium parvum (golden algae) and comparing it to samples collected from recent freshwater bloom and fish kill events in North America. Toxicon, 2010, 55 (7), 1396-1404. PMID: 20184911. VIEW
  • Cichewicz, R. H.; Henrikson, J. C.; Wang, X.; Branscum, K. M. Strategies for accessing microbial secondary metabolites from silent biosynthetic pathwaysManual of Industrial Microbiology and Biotechnology, 3rd edition, Baltz, R. H.; Demain, A. L.; Davies, J. E., Eds. ASM Press: Washington, D.C., 2010; pp 78-95.
  • Cichewicz, R. H.; Hambright, K. D. A revised amino group pKa for prymnesins does not provide decisive evidence for a pH-dependent mechanism of Prymnesium parvum toxicity. Toxicon, 2010, 55 (5), 1035-1037. PMID: 20223344. VIEW
  • Cichewicz, R. H. Epigenome manipulation as a pathway to new natural product scaffolds and their congeners. Natural Product Reports, 2010, 27 (1), 11-22. PMID: 20024091. VIEW

2009

  • Sena, J. G.; Nimmo, S. L.; Xavier, H. S.; Barbosa, J. M.; Cichewicz, R. H. Phenylethanoid and lignan glycosides from polar extracts of Lantana, a genus of verbenaceous plants widely used in traditional herbal therapies. Journal of Natural Products, 2009, 72 (7), 1344-1347. PMID: 19485331. VIEW
  • Henrikson, J. C.; Hoover, A. R.; Joyner, P. M.; Cichewicz, R. H. A chemical epigenetics approach for engineering the in situ biosynthesis of a cryptic natural product from Aspergillus niger. Organic & Biomolecular Chemistry, 2009, 7 (3), 435-438. PMID: 19156306. VIEW
  • Fisch, K. M.; Gillaspy, A. F.; Gipson, M.; Henrikson, J. C.; Hoover, A. R.; Jackson, L.; Najar, F. Z.; Wagele, H.; Cichewicz, R. H. Chemical induction of silent biosynthetic pathway transcription in Aspergillus niger. Journal of Industrial Microbiology & Biotechnology2009, 36 (9), 1199-1213. PMID: 19521728. VIEW

2008

  • Williams, R. B.; Henrikson, J. C.; Hoover, A. R.; Lee, A. E.; Cichewicz, R. H. Epigenetic remodeling of the fungal secondary metabolome. Organic & Biomolecular Chemistry, 2008, 6 (11), 1895-1897. PMID: 18480899. VIEW
  • Amagata, T.; Johnson, T. A.; Cichewicz, R. H.; Tenney, K.; Mooberry, S. L.; Media, J.; Edelstein, M.; Valeriote, F. A.; Crews, P. Interrogating the bioactive pharmacophore of the latrunculin chemotype by investigating the metabolites of two taxonomically unrelated sponges. Journal of Medicinal Chemistry, 2008, 51 (22), 7234-7242. PMID: 18942825. VIEW

2007

  • Williams, R. B.; Gutekunst, W. R.; Joyner, P. M.; Duan, W.; Li, Q.; Ross, C. A.; Williams, T. D.; Cichewicz, R. H. Bioactivity profiling with parallel mass spectrometry reveals an assemblage of green tea metabolites affording protection against human huntingtin and alpha-synuclein toxicity. Journal of Agricultural and Food Chemistry, 2007, 55 (23), 9450-9456. PMID: 17944533. VIEW